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Break-Induced Replication is a Source of Mutation Clusters Underlying Kataegis
Clusters of simultaneous multiple mutations can be a source of rapid change during carcinogenesis and evolution. Such mutation clusters have been recently shown to originate from DNA damage within long single-strand (ss) DNA formed at resected double-strand breaks and dysfunctional replication forks...
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| Publicado no: | Cell Rep |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4274036/ https://ncbi.nlm.nih.gov/pubmed/24882007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.04.053 |
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