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Break-Induced Replication and Genome Stability

Genetic instabilities, including mutations and chromosomal rearrangements, lead to cancer and other diseases in humans and play an important role in evolution. A frequent cause of genetic instabilities is double-strand DNA breaks (DSBs), which may arise from a wide range of exogeneous and endogeneou...

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Detalhes bibliográficos
Main Authors: Sakofsky, Cynthia J., Ayyar, Sandeep, Malkova, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3678771/
https://ncbi.nlm.nih.gov/pubmed/23767011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom2040483
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