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Repair of base damage within break-induced replication intermediates promotes kataegis associated with chromosome rearrangements
Break induced replication (BIR) is a double strand break repair pathway that can promote genetic instabilities similar to those observed in cancer. Instead of a replication fork, BIR is driven by a migration bubble where asynchronous synthesis between leading and lagging strands leads to accumulatio...
Zapisane w:
| Wydane w: | Nucleic Acids Res |
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| Główni autorzy: | , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Oxford University Press
2019
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6765108/ https://ncbi.nlm.nih.gov/pubmed/31392335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz651 |
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