Tracking break induced replication reveals its stalling at roadblocks

Break-induced replication (BIR) repairs one-ended double strand breaks (DSBs) similar to those formed by replication collapse or telomere erosion, and it has been implicated in the initiation of genome instability in cancer and other human disease(1,2). Previous studies have defined the enzymes requ...

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Publicat a:Nature
Autors principals: Liu, Liping, Yan, Zhenxin, Osia, Beth A, Twarowski, Jerzy, Sun, Luyang, Kramara, Juraj, Lee, Rosemary, Kumar, Sandeep, Elango, Rajula, Li, Hanzeng, Dang, Weiwei, Ira, Grzegorz, Malkova, Anna
Format: Artigo
Idioma:Inglês
Publicat: 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8219245/
https://ncbi.nlm.nih.gov/pubmed/33473214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-03172-w
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