Tracking break induced replication reveals its stalling at roadblocks

Break-induced replication (BIR) repairs one-ended double strand breaks (DSBs) similar to those formed by replication collapse or telomere erosion, and it has been implicated in the initiation of genome instability in cancer and other human disease(1,2). Previous studies have defined the enzymes requ...

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Bibliographic Details
Published in:Nature
Main Authors: Liu, Liping, Yan, Zhenxin, Osia, Beth A, Twarowski, Jerzy, Sun, Luyang, Kramara, Juraj, Lee, Rosemary, Kumar, Sandeep, Elango, Rajula, Li, Hanzeng, Dang, Weiwei, Ira, Grzegorz, Malkova, Anna
Format: Artigo
Language:Inglês
Published: 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8219245/
https://ncbi.nlm.nih.gov/pubmed/33473214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-03172-w
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