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Phosphorylation of Mutant Huntingtin at Serine 116 Modulates Neuronal Toxicity
Phosphorylation has been shown to have a significant impact on expanded huntingtin-mediated cellular toxicity. Several phosphorylation sites have been identified on the huntingtin (Htt) protein. To find new potential therapeutic targets for Huntington's Disease (HD), we used mass spectrometry t...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3914950/ https://ncbi.nlm.nih.gov/pubmed/24505464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088284 |
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