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Switching a Replication-Defective Adenoviral Vector into a Replication-Competent, Oncolytic Adenovirus

The adenovirus immediate early gene E1A initiates the program of viral gene transcription and reprograms multiple aspects of cell function and behavior. For adenoviral (Ad) vector-mediated gene transfer and therapy approaches, where replication-defective (RD) gene transfer is required, E1A has thus...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Nakashima, Hiroshi, Chiocca, E. Antonio
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911754/
https://ncbi.nlm.nih.gov/pubmed/24155386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02668-13
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