Novel Immunocompetent Murine Tumor Model for Evaluation of Conditionally Replication-Competent (Oncolytic) Murine Adenoviral Vectors

Oncolytic adenoviral vectors that express immunostimulatory transgenes are currently being evaluated in clinic. Preclinical testing of these vectors has thus far been limited to immunodeficient xenograft tumor models since human adenoviruses do not replicate effectively in murine tumor cells. The ef...

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Detaylı Bibliyografya
Asıl Yazarlar: Robinson, Michael, Li, Betty, Ge, Ying, Ko, Derek, Yendluri, Satya, Harding, Thomas, VanRoey, Melinda, Spindler, Katherine R., Jooss, Karin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 2009
Konular:
Gene Delivery
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663273/
https://ncbi.nlm.nih.gov/pubmed/19193803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02561-08
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