TMOD-16. A NOVEL ADENOVIRAL-PERMISSIVE, IMMUNOCOMPETENT HAMSTER GLIOMA MODEL TO EVALUATE ONCOLYTIC ADENOVIRAL THERAPY

Oncolytic adenoviruses, including Delta-24-RGD, target tumors by direct tumor cell oncolysis and by activation of an anti-tumor immune response. Due to the species selectivity of oncolytic adenoviruses, there is currently no single preclinical animal model of glioma that supports viral replication,...

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Publicat a:Neuro Oncol
Autors principals: Phillips, Lynette, Gumin, Joy, Li, Shoudong, Daou, Marc, Ledbetter, Daniel, Hossain, Anwar, Kerrigan, Brittany Parker, Gomez-Manzano, Candelaria, Fueyo, Juan, Lang, Frederick
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
Matèries:
Tumor Models
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651353/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.967
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