Characterization of the Recombinant Adenovirus Vector AdYB-1: Implications for Oncolytic Vector Development

Conditionally replicating adenoviruses are a promising new modality for the treatment of cancer. However, early clinical trials demonstrate that the efficacy of current vectors is limited. Interestingly, DNA replication and production of viral particles do not always correlate with virus-mediated ce...

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Bibliographic Details
Main Authors: Glockzin, Gabriel, Mantwill, Klaus, Jurchott, Karsten, Bernshausen, Alexandra, Ladhoff, Axel, Royer, Hans-Dieter, Gansbacher, Bernd, Holm, Per Sonne
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
Subjects:
Gene Delivery
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1440461/
https://ncbi.nlm.nih.gov/pubmed/16571807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.8.3904-3911.2006
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