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YB-1 dependent oncolytic adenovirus efficiently inhibits tumor growth of glioma cancer stem like cells
BACKGROUND: The brain cancer stem cell (CSC) model describes a small subset of glioma cells as being responsible for tumor initiation, conferring therapy resistance and tumor recurrence. In brain CSC, the PI3-K/AKT and the RAS/mitogen activated protein kinase (MAPK) pathways are found to be activate...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3848904/ https://ncbi.nlm.nih.gov/pubmed/24044901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-11-216 |
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