YB-1 dependent oncolytic adenovirus efficiently inhibits tumor growth of glioma cancer stem like cells

BACKGROUND: The brain cancer stem cell (CSC) model describes a small subset of glioma cells as being responsible for tumor initiation, conferring therapy resistance and tumor recurrence. In brain CSC, the PI3-K/AKT and the RAS/mitogen activated protein kinase (MAPK) pathways are found to be activate...

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Dettagli Bibliografici
Autori principali: Mantwill, Klaus, Naumann, Ulrike, Seznec, Janina, Girbinger, Vroni, Lage, Hermann, Surowiak, Pawel, Beier, Dagmar, Mittelbronn, Michel, Schlegel, Jürgen, Holm, Per Sonne
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3848904/
https://ncbi.nlm.nih.gov/pubmed/24044901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-11-216
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