STAT3/5 Inhibitors Suppress Proliferation in Bladder Cancer and Enhance Oncolytic Adenovirus Therapy

The JAK-STAT signalling pathway regulates cellular processes like cell division, cell death and immune regulation. Dysregulation has been identified in solid tumours and STAT3 activation is a marker for poor outcome. The aim of this study was to explore potential therapeutic strategies by targeting...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Hindupur, Sruthi V., Schmid, Sebastian C., Koch, Jana Annika, Youssef, Ahmed, Baur, Eva-Maria, Wang, Dongbiao, Horn, Thomas, Slotta-Huspenina, Julia, Gschwend, Juergen E., Holm, Per Sonne, Nawroth, Roman
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7043223/
https://ncbi.nlm.nih.gov/pubmed/32046095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21031106
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