Characterization of the Recombinant Adenovirus Vector AdYB-1: Implications for Oncolytic Vector Development

Conditionally replicating adenoviruses are a promising new modality for the treatment of cancer. However, early clinical trials demonstrate that the efficacy of current vectors is limited. Interestingly, DNA replication and production of viral particles do not always correlate with virus-mediated ce...

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Autori principali: Glockzin, Gabriel, Mantwill, Klaus, Jurchott, Karsten, Bernshausen, Alexandra, Ladhoff, Axel, Royer, Hans-Dieter, Gansbacher, Bernd, Holm, Per Sonne
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2006
Soggetti:
Gene Delivery
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1440461/
https://ncbi.nlm.nih.gov/pubmed/16571807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.8.3904-3911.2006
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