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Oncolytic Adenovirus: Strategies and Insights for Vector Design and Immuno-Oncolytic Applications

Adenoviruses (Ad) are commonly used both experimentally and clinically, including oncolytic virotherapy applications. In the clinical area, efficacy is frequently hampered by the high rates of neutralizing immunity, estimated as high as 90% in some populations that promote vector clearance and limit...

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Bibliografische gegevens
Gepubliceerd in:Viruses
Hoofdauteurs: Uusi-Kerttula, Hanni, Hulin-Curtis, Sarah, Davies, James, Parker, Alan L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4664994/
https://ncbi.nlm.nih.gov/pubmed/26610547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v7112923
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