Histone deacetylase inhibitor trichostatin A sensitises cisplatin-resistant ovarian cancer cells to oncolytic adenovirus

Ovarian cancer is often termed a silent killer due to the late onset of symptoms. Whilst patients initially respond to chemotherapy, they rapidly develop chemo-resistance. Oncolytic adenoviruses (OAds) are promising anti-cancer agents engineered to “hijack” the unique molecular machinery of cancer c...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Hulin-Curtis, Sarah L., Davies, James A., Jones, Rachel, Hudson, Emma, Hanna, Louise, Chester, John D., Parker, Alan L.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995174/
https://ncbi.nlm.nih.gov/pubmed/29899862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25242
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