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Species D Adenoviruses as Oncolytic Viral Vectors

Oncolytic adenoviruses (Ad) have shown promising results in the therapeutic treatment of cancer. Ad type 5 (Ad5) is the most extensively utilized Ad type. However, several limitations exist to using Ad5 as an oncolytic virus, including high levels of anti-Ad5 neutralizing antibodies in the populatio...

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Bibliographic Details
Published in:Viruses
Main Authors: Bullard, Brianna L., Corder, Brigette N., Weaver, Eric A.
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7762200/
https://ncbi.nlm.nih.gov/pubmed/33291224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12121399
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