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Regulation of Ras Localization and Cell Transformation by Evolutionarily Conserved Palmitoyltransferases
Ras can act on the plasma membrane (PM) to mediate extracellular signaling and tumorigenesis. To identify key components controlling Ras PM localization, we performed an unbiased screen to seek Schizosaccharomyces pombe mutants with reduced PM Ras. Five mutants were found with mutations affecting th...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3911504/ https://ncbi.nlm.nih.gov/pubmed/24248599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01248-13 |
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