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Regulation of Ras Localization and Cell Transformation by Evolutionarily Conserved Palmitoyltransferases

Ras can act on the plasma membrane (PM) to mediate extracellular signaling and tumorigenesis. To identify key components controlling Ras PM localization, we performed an unbiased screen to seek Schizosaccharomyces pombe mutants with reduced PM Ras. Five mutants were found with mutations affecting th...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Young, Evelin, Zheng, Ze-Yi, Wilkins, Angela D., Jeong, Hee-Tae, Li, Min, Lichtarge, Olivier, Chang, Eric C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911504/
https://ncbi.nlm.nih.gov/pubmed/24248599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01248-13
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