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UET: a database of evolutionarily-predicted functional determinants of protein sequences that cluster as functional sites in protein structures

The structure and function of proteins underlie most aspects of biology and their mutational perturbations often cause disease. To identify the molecular determinants of function as well as targets for drugs, it is central to characterize the important residues and how they cluster to form functiona...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Lua, Rhonald C., Wilson, Stephen J., Konecki, Daniel M., Wilkins, Angela D., Venner, Eric, Morgan, Daniel H., Lichtarge, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702906/
https://ncbi.nlm.nih.gov/pubmed/26590254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1279
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