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Association rate constants of ras-effector interactions are evolutionarily conserved.
Evolutionary conservation of protein interaction properties has been shown to be a valuable indication for functional importance. Here we use homology interface modeling of 10 Ras-effector complexes by selecting ortholog proteins from 12 organisms representing the major eukaryotic branches, except p...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science (PLoS)
2008-12-01
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| Colecção: | PLoS Computational Biology |
| Acesso em linha: | http://europepmc.org/articles/PMC2588540?pdf=render |
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