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Inhibition of Ras-Effector Interaction by Cyclic Peptides

A combinatorial library of 6 × 10(6) cyclic peptides was synthesized in the one bead-two compound format, with each bead displaying a unique cyclic peptide on its surface and a linear peptide encoding tag in its interior. Screening of the library against K-Ras identified compounds that bound K-Ras w...

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Hlavní autoři: Wu, Xianghong, Upadhyaya, Punit, Villalona-Calero, Miguel A., Briesewitz, Roger, Pei, Dehua
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3621770/
https://ncbi.nlm.nih.gov/pubmed/23585920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C2MD20329D
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