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Discovery of a Direct Ras Inhibitor by Screening a Combinatorial Library of Cell-Permeable Bicyclic Peptides
[Image: see text] Cyclic peptides have great potential as therapeutic agents and research tools. However, their applications against intracellular targets have been limited, because cyclic peptides are generally impermeable to the cell membrane. It was previously shown that fusion of cyclic peptides...
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| Pubblicato in: | ACS Comb Sci |
|---|---|
| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American
Chemical Society
2015
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4710893/ https://ncbi.nlm.nih.gov/pubmed/26645887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscombsci.5b00164 |
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