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Discovery of a Direct Ras Inhibitor by Screening a Combinatorial Library of Cell-Permeable Bicyclic Peptides

[Image: see text] Cyclic peptides have great potential as therapeutic agents and research tools. However, their applications against intracellular targets have been limited, because cyclic peptides are generally impermeable to the cell membrane. It was previously shown that fusion of cyclic peptides...

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Bibliografske podrobnosti
izdano v:ACS Comb Sci
Main Authors: Trinh, Thi B., Upadhyaya, Punit, Qian, Ziqing, Pei, Dehua
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2015
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4710893/
https://ncbi.nlm.nih.gov/pubmed/26645887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscombsci.5b00164
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