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Cell-Permeable Bicyclic Peptide Inhibitors against Intracellular Proteins

[Image: see text] Cyclic peptides have great potential as therapeutic agents and research tools but are generally impermeable to the cell membrane. Fusion of cyclic peptides with a cyclic cell-penetrating peptide produces bicyclic peptides that are cell-permeable and retain the ability to recognize...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Lian, Wenlong, Jiang, Bisheng, Qian, Ziqing, Pei, Dehua
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227718/
https://ncbi.nlm.nih.gov/pubmed/24972263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja503710n
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