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Inhibition of Ras-Effector Interaction by Cyclic Peptides
A combinatorial library of 6 × 10(6) cyclic peptides was synthesized in the one bead-two compound format, with each bead displaying a unique cyclic peptide on its surface and a linear peptide encoding tag in its interior. Screening of the library against K-Ras identified compounds that bound K-Ras w...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3621770/ https://ncbi.nlm.nih.gov/pubmed/23585920 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C2MD20329D |
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