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TRPV4-mediated mechanotransduction regulates the metabolic response of chondrocytes to dynamic loading

Mechanical loading of joints plays a critical role in maintaining the health and function of articular cartilage. The mechanism(s) of chondrocyte mechanotransduction are not fully understood, but could provide important insights into new physical or pharmacologic therapies for joint diseases. Transi...

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Detalhes bibliográficos
Main Authors: O’Conor, Christopher J., Leddy, Holly A., Benefield, Halei C., Liedtke, Wolfgang B., Guilak, Farshid
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910592/
https://ncbi.nlm.nih.gov/pubmed/24474754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1319569111
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