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TRPV4-mediated mechanotransduction regulates the metabolic response of chondrocytes to dynamic loading

Mechanical loading of joints plays a critical role in maintaining the health and function of articular cartilage. The mechanism(s) of chondrocyte mechanotransduction are not fully understood, but could provide important insights into new physical or pharmacologic therapies for joint diseases. Transi...

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Autors principals: O’Conor, Christopher J., Leddy, Holly A., Benefield, Halei C., Liedtke, Wolfgang B., Guilak, Farshid
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910592/
https://ncbi.nlm.nih.gov/pubmed/24474754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1319569111
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