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Unraveling the mechanism by which TRPV4 mutations cause skeletal dysplasias

Transient Receptor Potential Vanilloid 4 (TRPV4) is a mechano- and osmosensitive cation channel that is highly expressed in chondrocytes, the cells in cartilage. A large number of mutations in TRPV4 have been linked to skeletal dysplasias, and the goal of this addendum is to shed light on the mechan...

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Bibliografiske detaljer
Udgivet i:Rare Dis
Main Authors: Leddy, Holly A, McNulty, Amy L, Guilak, Farshid, Liedtke, Wolfgang
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755236/
https://ncbi.nlm.nih.gov/pubmed/26942100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/2167549X.2014.962971
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