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Collagen VI regulates pericellular matrix properties, chondrocyte swelling, and mechanotransduction in articular cartilage

OBJECTIVE: Mechanical factors play a critical role in the physiology and pathology of articular cartilage, although the mechanisms of mechanical signal transduction are not fully understood. We examined the hypothesis that type VI collagen is necessary for mechanotransduction in articular cartilage,...

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Detalhes bibliográficos
Publicado no:Arthritis Rheumatol
Main Authors: Zelenski, Nicole A., Leddy, Holly A., Sanchez-Adams, Johannah, Zhang, Jinzi, Bonaldo, Paolo, Liedtke, Wolfgang, Guilak, Farshid
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4414817/
https://ncbi.nlm.nih.gov/pubmed/25604429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.39034
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