Kinetic Differences in the Induction of Interferon Stimulated Genes by Interferon-α and IL28B are altered by Infection with Hepatitis C Virus

Several genome-wide association studies (GWAS) have identified a genetic polymorphism associated with the gene locus for interleukin 28B (IL28B), a type III interferon (IFN), as a major predictor of clinical outcome in hepatitis C. Antiviral effects of the type III IFN family have previously been sh...

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Auteurs principaux: Jilg, Nikolaus, Lin, Wenyu, Hong, Jian, Schaefer, Esperance A., Wolski, David, Meixong, James, Goto, Kaku, Brisac, Cynthia, Chusri, Pattranuch, Fusco, Dahlene N., Chevaliez, Stephane, Luther, Jay, Kumthip, Kattareeya, Urban, Thomas J., Peng, Lee F., Lauer, Georg M., Chung, Raymond T.
Format: Artigo
Langue:Inglês
Publié: 2014
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3909557/
https://ncbi.nlm.nih.gov/pubmed/23913866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26653
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