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SOCS1 Abrogates IFN’s Antiviral Effect on Hepatitis C Virus Replication

Suppressor of Cytokine Signaling 1 (SOCS1) and Suppressor of Cytokine Signaling 3 (SOCS3) have been thought to block type I interferon (IFN) signaling. We have previously reported that SOCS3 suppresses HCV replication in an mTOR-dependent manner. However, the relationship between SOCS1 and HCV repli...

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Detalhes bibliográficos
Main Authors: Shao, Run-Xuan, Zhang, Leiliang, Hong, Zhi, Goto, Kaku, Cheng, Du, Chen, Wen-Chi, Jilg, Nikolaus, Kumthip, Kattareeya, Fusco, Dahlene N., Peng, Lee F., Chung, Raymond T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3764487/
https://ncbi.nlm.nih.gov/pubmed/23237992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2012.12.001
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