IL28B inhibits Hepatitis C virus replication through the JAK-STAT pathway

BACKGROUND AND AIMS: The combination of pegylated interferon (IFN) α and ribavirin (RBV) is standard therapy for patients with chronic HCV infection. However, it produces a sustained virologic response (SVR) in only half of treated individuals and is associated with significant side effects. Recentl...

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Hlavní autoři: Zhang, Leiliang, Jilg, Nikolaus, Shao, Run-Xuan, Lin, Wenyu, Fusco, Dahlene N., Zhao, Hong, Goto, Kaku, Peng, Lee F., Chen, Wen-Chi, Chung, Raymond T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3068235/
https://ncbi.nlm.nih.gov/pubmed/21147189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2010.11.019
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