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A yeast phenomic model for the gene interaction network modulating CFTR-ΔF508 protein biogenesis

BACKGROUND: The overall influence of gene interaction in human disease is unknown. In cystic fibrosis (CF) a single allele of the cystic fibrosis transmembrane conductance regulator (CFTR-ΔF508) accounts for most of the disease. In cell models, CFTR-ΔF508 exhibits defective protein biogenesis and de...

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Xehetasun bibliografikoak
Egile Nagusiak: Louie, Raymond J, Guo, Jingyu, Rodgers, John W, White, Rick, Shah, Najaf A, Pagant, Silvere, Kim, Peter, Livstone, Michael, Dolinski, Kara, McKinney, Brett A, Hong, Jeong, Sorscher, Eric J, Bryan, Jennifer, Miller, Elizabeth A, Hartman, John L
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3906889/
https://ncbi.nlm.nih.gov/pubmed/23270647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm404
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