Helq acts in parallel to Fancc to suppress replication-associated genome instability

HELQ is a superfamily 2 DNA helicase found in archaea and metazoans. It has been implicated in processing stalled replication forks and in repairing DNA double-strand breaks and inter-strand crosslinks. Though previous studies have suggested the possibility that HELQ is involved in the Fanconi anemi...

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Detalhes bibliográficos
Main Authors: Luebben, Spencer W., Kawabata, Tsuyoshi, Akre, Monica K., Lee, Wai Long, Johnson, Charles S., O’Sullivan, M. Gerard, Shima, Naoko
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Genome Integrity, Repair and Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3905894/
https://ncbi.nlm.nih.gov/pubmed/24005041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt676
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