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A concomitant loss of dormant origins and FANCC exacerbates genome instability by impairing DNA replication fork progression

Accumulating evidence suggests that dormant DNA replication origins play an important role in the recovery of stalled forks. However, their functional interactions with other fork recovery mechanisms have not been tested. We previously reported intrinsic activation of the Fanconi anemia (FA) pathway...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Luebben, Spencer W., Kawabata, Tsuyoshi, Johnson, Charles S., O'Sullivan, M. Gerard, Shima, Naoko
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Oxford University Press 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027174/
https://ncbi.nlm.nih.gov/pubmed/24589582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku170
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