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A concomitant loss of dormant origins and FANCC exacerbates genome instability by impairing DNA replication fork progression

Accumulating evidence suggests that dormant DNA replication origins play an important role in the recovery of stalled forks. However, their functional interactions with other fork recovery mechanisms have not been tested. We previously reported intrinsic activation of the Fanconi anemia (FA) pathway...

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Bibliografski detalji
Glavni autori: Luebben, Spencer W., Kawabata, Tsuyoshi, Johnson, Charles S., O'Sullivan, M. Gerard, Shima, Naoko
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027174/
https://ncbi.nlm.nih.gov/pubmed/24589582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku170
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