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A concomitant loss of dormant origins and FANCC exacerbates genome instability by impairing DNA replication fork progression
Accumulating evidence suggests that dormant DNA replication origins play an important role in the recovery of stalled forks. However, their functional interactions with other fork recovery mechanisms have not been tested. We previously reported intrinsic activation of the Fanconi anemia (FA) pathway...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4027174/ https://ncbi.nlm.nih.gov/pubmed/24589582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku170 |
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