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Leukemia and chromosomal instability in aged Fancc−/− mice
Fanconi anemia (FA) is an inherited disorder of genomic instability associated with high risk of myelodysplasia and AML. Young mice deficient in FA core complex genes do not naturally develop cancer, hampering preclinical studies on malignant hematopoiesis in FA. Here we show that aging Fancc−/− mic...
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| 出版年: | Exp Hematol |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5131786/ https://ncbi.nlm.nih.gov/pubmed/26860989 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2016.01.009 |
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