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A reduction of licensed origins reveals strain-specific replication dynamics in mice

Replication origin licensing builds a fundamental basis for DNA replication in all eukaryotes. This occurs during the late M to early G1 phases in which chromatin is licensed by loading of the MCM2-7 complex, an essential component of the replicative helicase. In the following S phase, only a minor...

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Bibliographic Details
Main Authors: Kawabata, Tsuyoshi, Yamaguchi, Satoru, Buske, Tavanna, Luebben, Spencer W, Wallace, Marsha, Matise, Ilze, Schimenti, John C, Shima, Naoko
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528403/
https://ncbi.nlm.nih.gov/pubmed/21611832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00335-011-9333-7
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