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A reduction of licensed origins reveals strain-specific replication dynamics in mice
Replication origin licensing builds a fundamental basis for DNA replication in all eukaryotes. This occurs during the late M to early G1 phases in which chromatin is licensed by loading of the MCM2-7 complex, an essential component of the replicative helicase. In the following S phase, only a minor...
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Main Authors: | , , , , , , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
2011
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3528403/ https://ncbi.nlm.nih.gov/pubmed/21611832 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00335-011-9333-7 |
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