Targeting the cell cycle inhibitor p57(Kip2) promotes adult human β cell replication

Children with focal hyperinsulinism of infancy display a dramatic, non-neoplastic clonal expansion of β cells that have undergone mitotic recombination, resulting in paternal disomy of part of chromosome 11. This disomic region contains imprinted genes, including the gene encoding the cell cycle inh...

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Detaylı Bibliyografya
Asıl Yazarlar: Avrahami, Dana, Li, Changhong, Yu, Ming, Jiao, Yang, Zhang, Jia, Naji, Ali, Ziaie, Seyed, Glaser, Benjamin, Kaestner, Klaus H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2014
Konular:
Brief Report
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3904605/
https://ncbi.nlm.nih.gov/pubmed/24430183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI69519
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