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An essential role for Ink4 and Cip/Kip cell-cycle inhibitors in preventing replicative stress
Cell-cycle inhibitors of the Ink4 and Cip/Kip families are involved in cellular senescence and tumor suppression. These inhibitors are individually dispensable for the cell cycle and inactivation of specific family members results in increased proliferation and enhanced susceptibility to tumor devel...
Gespeichert in:
| Veröffentlicht in: | Cell Death Differ |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5072439/ https://ncbi.nlm.nih.gov/pubmed/26292757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.112 |
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