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Methylation of INK4 and CIP/KIP families of cyclin‐dependent kinase inhibitor in chronic lymphocytic leukaemia in Chinese patients
BACKGROUND: INK4 (p15, p16, p18 and p19) and CIP/KIP (p21, p27 and p57) are two families of cyclin‐dependent kinase inhibitors (CKI) targeting CDK4/6 and CDK2, respectively. AIM: To study the role of methylation in the inactivation of CKI in chronic lymphocytic leukaemia (CLL). MATERIALS AND METHODS...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMJ Group
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1860467/ https://ncbi.nlm.nih.gov/pubmed/16565223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jcp.2005.035089 |
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