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The Role of the LH Subdomain in the Function of the Cip/Kip Cyclin-Dependent Kinase Regulators
The Cip/Kip protein family, which includes p27, p21, and p57, modulates the activity of cyclin-dependent kinases (Cdks). A domain within these proteins, termed the kinase inhibitory domain (KID), is necessary and sufficient for Cdk inhibition. The KID consists of a cyclin-binding subdomain (termed D...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3093569/ https://ncbi.nlm.nih.gov/pubmed/21575583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.04.014 |
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