The Role of the LH Subdomain in the Function of the Cip/Kip Cyclin-Dependent Kinase Regulators

The Cip/Kip protein family, which includes p27, p21, and p57, modulates the activity of cyclin-dependent kinases (Cdks). A domain within these proteins, termed the kinase inhibitory domain (KID), is necessary and sufficient for Cdk inhibition. The KID consists of a cyclin-binding subdomain (termed D...

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Bibliographische Detailangaben
Hauptverfasser: Otieno, Steve, Grace, Christy R., Kriwacki, Richard W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2011
Schlagworte:
Protein
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093569/
https://ncbi.nlm.nih.gov/pubmed/21575583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.04.014
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