The activity and stability of the intrinsically disordered Cip/Kip protein family are regulated by non-receptor tyrosine kinases

The Cip/Kip family of cyclin-dependent kinase (Cdk) inhibitors includes p21(Cip1), p27(Kip1) and p57(Kip2). Their kinase inhibitory activities are mediated by a homologous N-terminal kinase-inhibitory domain (KID). The Cdk inhibitory activity and stability of p27 have been shown to be regulated by a...

Full description

Saved in:
Bibliographic Details
Published in:J Mol Biol
Main Authors: Huang, Yongqi, Yoon, Mi-Kyung, Otieno, Steve, Lelli, Moreno, Kriwacki, Richard W.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4297576/
https://ncbi.nlm.nih.gov/pubmed/25463440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2014.11.011
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items