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The activity and stability of the intrinsically disordered Cip/Kip protein family are regulated by non-receptor tyrosine kinases
The Cip/Kip family of cyclin-dependent kinase (Cdk) inhibitors includes p21(Cip1), p27(Kip1) and p57(Kip2). Their kinase inhibitory activities are mediated by a homologous N-terminal kinase-inhibitory domain (KID). The Cdk inhibitory activity and stability of p27 have been shown to be regulated by a...
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| Publicado no: | J Mol Biol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4297576/ https://ncbi.nlm.nih.gov/pubmed/25463440 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2014.11.011 |
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