IGFBP3 promotes esophageal cancer growth by suppressing oxidative stress in hypoxic tumor microenvironment

Insulin-like growth factor binding protein 3 (IGFBP3), a hypoxia-inducible gene, regulates a variety of cellular processes including cell proliferation, senescence, apoptosis and epithelial-mesenchymal transition (EMT). IGFBP3 has been linked to the pathogenesis of cancers. Most previous studies foc...

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Bibliographische Detailangaben
Hauptverfasser: Natsuizaka, Mitsuteru, Kinugasa, Hideaki, Kagawa, Shingo, Whelan, Kelly A, Naganuma, Seiji, Subramanian, Harry, Chang, Sanders, Nakagawa, Kei J, Rustgi, Naryan L, Kita, Yoshiaki, Natsugoe, Shoji, Basu, Devraj, Gimotty, Phyllis A, Klein-Szanto, Andres J, Diehl, J Alan, Nakagawa, Hiroshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2014
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3902230/
https://ncbi.nlm.nih.gov/pubmed/24482736
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