A NOTCH3-mediated squamous cell differentiation program limits expansion of EMT competent cells that express the ZEB transcription factors

Zinc finger E-box binding (ZEB) proteins ZEB1 and ZEB2 are transcription factors essential in transforming growth factor (TGF)-β-mediated senescence, epithelial to mesenchymal transition (EMT) and cancer stem cell function. ZEBs are negatively regulated by members of the miR-200 microRNA family, but...

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Detalhes bibliográficos
Main Authors: Ohashi, Shinya, Natsuizaka, Mitsuteru, Naganuma, Seiji, Kagawa, Shingo, Kimura, Sotai, Itoh, Hiroshi, Kalman, Ross A., Nakagawa, Momo, Darling, Douglas S., Basu, Devraj, Gimotty, Phyllis A., Klein-Szanto, Andres J, Diehl, J. Alan, Herlyn, Meenhard, Nakagawa, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206139/
https://ncbi.nlm.nih.gov/pubmed/21890822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-0846
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