The Hippo Pathway Effectors TAZ/YAP Regulate Dicer Expression and MicroRNA Biogenesis through Let-7

MicroRNAs (miRNAs) are genome-encoded small double-stranded RNAs that have emerged as key regulators of gene expression and are implicated in most aspects of human development and disease. Canonical miRNA biogenesis involves processing of ∼70-nucleotide pre-miRNA hairpins by Dicer to generate mature...

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Bibliographische Detailangaben
Hauptverfasser: Chaulk, Steven G., Lattanzi, Victoria J., Hiemer, Samantha E., Fahlman, Richard P., Varelas, Xaralabos
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2014
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Reports
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900939/
https://ncbi.nlm.nih.gov/pubmed/24324261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C113.529362
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