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The Transcriptional Regulators TAZ and YAP Direct Transforming Growth Factor β-induced Tumorigenic Phenotypes in Breast Cancer Cells

Uncontrolled transforming growth factor-β (TGFβ) signaling promotes aggressive metastatic properties in late-stage breast cancers. However, how TGFβ-mediated cues are directed to induce tumorigenic events is poorly understood, particularly given that TGFβ has clear tumor suppressing activity in othe...

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Main Authors: Hiemer, Samantha E., Szymaniak, Aleksander D., Varelas, Xaralabos
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036353/
https://ncbi.nlm.nih.gov/pubmed/24648515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.529115
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