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Crumbs3-mediated polarity directs airway epithelial cell fate through the Hippo pathway effector Yap
Epithelial cells undergo dynamic polarity changes as organs pattern, but the relationship between epithelial polarity and cell fate is poorly understood. Using the developing lung as a model, we have found that distinct alterations in apical-basal polarity dictate airway epithelial differentiation....
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| Publicado no: | Dev Cell |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4536126/ https://ncbi.nlm.nih.gov/pubmed/26235047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2015.06.020 |
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