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The Hippo Pathway Effector Yap Controls Patterning and Differentiation of Airway Epithelial Progenitors

How epithelial progenitor cells integrate local signals to balance expansion with differentiation during organogenesis is still little understood. Here we provide evidence that the Hippo pathway effector Yap is a key regulator of this process in the developing lung. We show that when epithelial tubu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Dev Cell
Hauptverfasser: Mahoney, John E., Mori, Munemasa, Szymaniak, Aleksander D., Varelas, Xaralabos, Cardoso, Wellington V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6331061/
https://ncbi.nlm.nih.gov/pubmed/25043473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2014.06.003
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