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The Hippo Pathway Effector Yap Controls Patterning and Differentiation of Airway Epithelial Progenitors

How epithelial progenitor cells integrate local signals to balance expansion with differentiation during organogenesis is still little understood. Here we provide evidence that the Hippo pathway effector Yap is a key regulator of this process in the developing lung. We show that when epithelial tubu...

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Detalhes bibliográficos
Publicado no:Dev Cell
Main Authors: Mahoney, John E., Mori, Munemasa, Szymaniak, Aleksander D., Varelas, Xaralabos, Cardoso, Wellington V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6331061/
https://ncbi.nlm.nih.gov/pubmed/25043473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2014.06.003
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