Region-specific deficits in dopamine, but not norepinephrine, signaling in a novel A30P α-synuclein BAC transgenic mouse()

Parkinson's disease (PD) is a neurodegenerative disorder classically characterized by the death of dopamine (DA) neurons in the substantia nigra pars compacta and by intracellular Lewy bodies composed largely of α-synuclein. Approximately 5–10% of PD patients have a familial form of Parkinsonis...

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Autors principals: Taylor, Tonya N., Potgieter, Dawid, Anwar, Sabina, Senior, Steven L., Janezic, Stephanie, Threlfell, Sarah, Ryan, Brent, Parkkinen, Laura, Deltheil, Thierry, Cioroch, Milena, Livieratos, Achilleas, Oliver, Peter L., Jennings, Katie A., Davies, Kay E., Ansorge, Olaf, Bannerman, David M., Cragg, Stephanie J., Wade-Martins, Richard
Format: Artigo
Idioma:Inglês
Publicat: Academic Press 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3898275/
https://ncbi.nlm.nih.gov/pubmed/24121116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2013.10.005
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