Region-specific deficits in dopamine, but not norepinephrine, signaling in a novel A30P α-synuclein BAC transgenic mouse()

Parkinson's disease (PD) is a neurodegenerative disorder classically characterized by the death of dopamine (DA) neurons in the substantia nigra pars compacta and by intracellular Lewy bodies composed largely of α-synuclein. Approximately 5–10% of PD patients have a familial form of Parkinsonis...

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Main Authors: Taylor, Tonya N., Potgieter, Dawid, Anwar, Sabina, Senior, Steven L., Janezic, Stephanie, Threlfell, Sarah, Ryan, Brent, Parkkinen, Laura, Deltheil, Thierry, Cioroch, Milena, Livieratos, Achilleas, Oliver, Peter L., Jennings, Katie A., Davies, Kay E., Ansorge, Olaf, Bannerman, David M., Cragg, Stephanie J., Wade-Martins, Richard
Formato: Artigo
Idioma:Inglês
Publicado: Academic Press 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3898275/
https://ncbi.nlm.nih.gov/pubmed/24121116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2013.10.005
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